POSTECH ACADEMY-INDUSTRY FOUNDATION;INSTITUTE FOR BASIC SCIENCE
发明人:
Charles D. SURH,Jun-Young LEE
申请号：
US16616172
公开号：
US20200140538A1
申请日:
2018.05.25
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Provided is an antibody that binds to human interleukin-2 (hIL-2), and more particularly to an anti-hIL-2 antibody that binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25.The anti-hIL-2 antibody of the subject matter binds specifically to a particular epitope of hIL-2, thereby inhibiting the binding of the hIL-2 to CD25, thereby minimizing expansion of Treg cells. In addition, it stimulates the CD8+ T cells and NK cells that exhibit anti-tumor activity. Thus, the anti-hIL-2 antibody of the present invention is useful as a new anticancer therapeutic agent.
