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Modified CAR-T
专利权人:
TC Biopharm Limited
发明人:
Agapitos Patakas,Timothy London,Emilio Cosimo
申请号:
US16649982
公开号:
US20200289564A1
申请日:
2018.10.01
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to gamma delta (γδ) T cells and/or Natural Killer (NK) cells expressing constructs to provide for the expression of a Chimeric Antigen Receptor (CAR) incorporating the signalling domain of FCY Receptors. Suitably the invention also relates to constructs to provide such CARs and methods for introducing such CARs into cells and expressing such CARs in cells comprising receptors of gamma delta (γδ) T cells and/or Natural Killer (NK) cells.
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