UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY
发明人:
MA, JIANJIE,WEISLEDER, NOAH
申请号：
EP09798748
公开号：
EP2320931A4
申请日:
2009.07.16
申请国别(地区):
EP
年份:
2013
代理人:
摘要：
Disclosed herein are compositions and methods for treatment of muscle dysfunction (including sarcopenia) and other diseases involving skeletal muscle, including age-related muscle dysfunction. In addition, the invention relates to therapeutic compositions comprising nucleotides and/or polypeptides of the invention in combination with a pharmaceutically acceptable carrier, wherein the composition facilitates the treatment of skeletal muscle disorder, including those related to thr normal aging process. Moreover, the invention relates to the treatment and/or prevention of pathological conditions associated with altered intracellular Ca2+ regulation and disrupted membrane structure that occurs when the expression levels of MG29 are reduced.
