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PROTÉINES D'HÉMAGGLUTININE DE LA GRIPPE ET MÉTHODES ASSOCIÉES
专利权人:
Avatar Medical; LLC
发明人:
申请号:
EP14799913.0
公开号:
EP3027640B1
申请日:
2014.08.02
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
In some embodiments the present invention provides influenza hemagglutinin ("HA") polypeptides, proteins, and protein complexes that comprise a stalk domain that is engineered to facilitate maintenance of its native trimeric conformation, even if the head domain of the HA protein is removed or disrupted. In some embodiments, the present invention provides compositions comprising such polypeptides, proteins, and protein complexes, and methods of use of such proteins and compositions, for example as vaccine immunogens.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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