BURKE, DAVID J.,BUCKLEY, SHAUN E.,LEHRMAN, SHERWOOD RUSS,O'CONNOR, BARBARA HORSEY,CALLAWAY, JAMES,PHILLIPS, CHRISTOPHER
申请号：
CA2515444
公开号：
CA2515444C
申请日:
2004.02.09
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
A stable aqueous pharmaceutical formulation comprising a therapeuticallyeffective amount of an antibody, polysorbate 80, a buffer which inhibitspolysorbate oxidation is described along with methods of making thepreparation. Also described are formulations with high antibody concentrationswhich maintain fixed volumes and which may be used on patients of variableweight.
