Described herein is a sterile protective cover comprising an intracameral therapeutic agent delivery device in the form of a pen-injector comprising a cartridge container for dispensing multiple doses of a medicament, coupled to an actuation assembly within a housing. In some forms a needle assembly is coupled to the distal end of the cartridge container, provided with a removable cap received within the housing will be in optional pre-sterile or no-sterile condition. Use of such device for the prevention or treatment of ocular conditions or diseases is also disclosed. A sterile protective cover may be combined with an ophthalmic device, wherein the sterile protective cover is made of plastic, polythene, polyethylene, resin, rubber, polystyrene, polypropylene, polycarbonate, nylon, or combination thereof.