This invention multiplication amiodaron of the tonnage which remedy is effective and multiplication also ranorajin of the tonnage which is effective remedy includes dosage, it is related to the manner of remedying the atrial fibrillation. In addition as for this invention, it is related to suitable medical supply prescription ones for that kind of dosage which is combined. In another aspect of this invention, manner in order to suppress the side effect whose amiodaron is not desirable is presented. The manner multiplication amiodaron of the dosage which remedy is effective and multiplication also ranorajin of the dosage which is effective remedy includes dosage.本発明は、相乗的な治療的に有効な量のアミオダロンおよび相乗的な治療的に有効な量のラノラジンの共投与を含む、心房細動の治療の方法に関連する。本発明はまた、そのような組み合わせた投与のために適当な医薬品処方物に関連する。本発明の別の局面において、アミオダロンの望ましくない副作用を抑制するための方法が提示される。その方法は、相乗的な治療的に有効な用量のアミオダロンおよび相乗的な治療的に有効な用量のラノラジンの共投与を含む。