NHO, YOUNG CHANG,노영창,PARK, JONG SEOK,박종석,LIM, YOUN MOOK,임윤묵,KANG, PHIL HYUN,강필현,HUH, KANG MOO,허강무,PARK, JEONG SOOK,박정숙,NHO, YOUNG CHANGKR,PARK, JONG SEOKKR,LIM, YOUN MOOKKR,KANG, PHIL HYUNKR,HUH, KANG MOOKR,PARK, JEONG SOOKKR
申请号:
KR1020130003308
公开号:
KR1020140091259A
申请日:
2013.01.11
申请国别(地区):
KR
年份:
2014
代理人:
摘要:
Provided in the present invention is a method for manufacturing a mucoadhesive hydrogel by adding diacrylated poloxamer which induces a crosslinkable functional group with a poloxamer and carbopol to an aqueous solution, and irradiating on the same. The method for manufacturing a mocoadhesive hydrogel of the present invention can improve mechanical properties of the mucoadhesive hydrogel manufactured by inducing a crosslinkable functional group with poloxamer, irradiating radiation, and cross linking.본 발명은 수용액에 폴록사머에 가교가능한 작용기를 도입한 디아크릴레이티드 폴록사머와 카보폴을 첨가하여 방사선을 조사하여 점막부착성 하이드로젤을 제조하는 방법을 제공한다.