LECLERC, CLAUDE,LASARTE SAGASTIBELZA, JUAN JOSE,GORRAIZ AYALA, MARTA,PRIETO VALTUENA, JESUS
申请号:
CA2612151
公开号:
CA2612151C
申请日:
2006.06.13
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
This invention relates to the use of a polypeptide in theproduction of an immunostimulatory agent, saidpolypeptide comprising a sequence corresponding to theEDA domain of fibronectin, a fragment of the EDA domainwhich can bind to TLR4 or a variant of said EDA domain ora fragment which can bind to TLR4 and which has ahomology of more than 70% with any form or naturalfragment of the EDA domain. The invention also relates tothe production methods and applications of said agent.