A machine for the cold sanification of medical devices comprises at least one sanification chamber (2) adapted to housing at least one medical device to be treated means (3) for supplying one or more sanification fluids comprising a plurality of hydraulic circuits (4 4 4") each having a drawing conduit (5 5 5") for the sanification fluids connectable to a respective reservoir (S S\ S") and a plurality of delivering conduits (6 6 6" ...) connected with the sanification chamber (2) for introducing the pressurized fluids therein means (7) for fluidically connecting one or more of the drawing conduits (6 6 6" ...) with corresponding inner channels of the device housed into the sanification chamber (2). The supplying means (3) comprise a central collector (9) interposed between the drawing conduits (5 5 5") and the delivering conduits (6 6 6" ...) for receiving from the first the fluids an to supply to each of the delivering conduits (6 6 6" ...) the sanification fluids at the substantially same pressure (P).
