INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 October 2018 (11.10.2018) WIPO I PCT omit VIII °nolo 110 Ho Ill ono mil (10) International Publication Number WO 2018/187473 Al (51) International Patent Classification: A61K 31/4523 (2006.01) A61P 31/00 (2006.01) A61K 31/454 (2006.01) A61K 31/4545 (2006.01) A61P 37/00 (2006.01) A61K 9/00 (2006.01) (21) International Application Number: PCT/US2018/026091 (22) International Filing Date: 04 April 2018 (04.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/482,134 05 April 2017 (05.04.2017) US (71) Applicant: ALKAHEST INC. [US/US]； 75 Shoreway Road, Suite D, San Carlos, CA 94070 (US). (72) Inventors: CORADINI, Laura； Boehringer Ingelheim Intn'l Gmbh Corporate Patents, Binger Str. 173, 55216 In- gelheim am Rhein (DE). JACKSON, Sam； 75 Shoreway Road, Suite D, San Carlos, CA 94070 (US). NIKOLICH, Karoly； 75 Shoreway Road, Suite D, San Carlos, CA 94070 (US). (74) Agent: KISSLING, Heather, R. et al.； Marshall, Gerstein & Borun LLP, 233 S. Wacker Drive, 6300 Willis Tower, Chicago, IL 60606-6357 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. Published: — with international search report (Art. 21(3)) 1-1 N N co 00 O C (84) Designated States (unless otherwise indicated, for every kind of regional protection available)
