Sonia Martinez Gonzalez;Rosa Maria Alvarez Escobar;Antonlo Rodriguez Hergueta;Francisco Ramos Lima;José Ignacio Martin Hernando;Joaquin Pastor Fernández
发明人:
Joaquin Pastor Fernández,Sonia Martinez Gonzalez,Rosa Maria Alvarez Escobar,Antonlo Rodriguez Hergueta,José Ignacio Martin Hernando,Francisco Ramos Lima
申请号：
US13574018
公开号：
US20130053371A1
申请日:
2011.01.24
申请国别(地区):
US
年份:
2013
代理人:
摘要：
There is provided compounds of formula (I), wherein A1, A4, A4a, A5, B1, B1a, B2, B2a, B3, B3a, B4, B4a and R3 have meanings given in the description, and pharmaceutically-acceptable esters, amides, solvates or salts thereof, which compounds are useful in the treatment of diseases in which inhibition of a protein or lipid kinase (e.g. a PI3-K and/or mTOR) is desired and/or required, and particularly in the treatment of cancer or a proliferative disease.
