GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
发明人:
HARLING, JOHN DAVID,TINWORTH, CHRISTOPHER
申请号:
CA3025744
公开号:
CA3025744A1
申请日:
2017.06.08
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A method of treating disorders associated with aberrant kinase activity, wherein the kinase is. IRAK3, GAK, TEC, PTK2B(PYK2), AURKA, RPS6KAKRSK3), MAPK9(JNK2), BTK, PTK2 or AKT2., said method comprising degrading said kinase using compounds of Formula (I): Target Protein Binder - Linker - IAP binder (I)