The present invention is directed to a self-penetrating percutaneous optical sensing device for obtaining and transmitting optical signal from intravascular fluid in a blood vessel, the device comprising: (a) an elongated hollow rigid sensor sheath 20 having a proximal end 21, a distal end 22 and a central channel extending along the sensor sheath, wherein the distal end 22 of the sensor sheath 20 is sufficiently sharpened to puncture a cutaneous barrier and the sensor sheath 20 has a sufficient length to allow the sensor sheath 20 to penetrate into intravascular space of a blood vessel (b) a flexible optical fiber 30 having a proximal end and a distal end situated coherently within the central channel of the sensor sheath 20 wherein the sensor sheath 20 covers a portion of the distal end of the flexible optical fiber 30 and wherein the distal end of the flexible optical fiber 30 aligns with the distal end 22 of the sensor sheath 20 and (c) an optical sensor 40 connected to the distal end of the flexible optical fiber 30 wherein optical signal generated at the optical sensor 40 can be transmitted from the optical sensor 40 to the proximal end of the flexible optical fiber 30 via the flexible optical fiber 30 and wherein the optical sensor 40 has direct access to the intravascular fluid of the blood vessel.Cette invention concerne un dispositif de détection optique percutané auto-perforant permettant dobtenir un signal optique provenant dun liquide intravasculaire dun vaisseau sanguin et de le transmettre, ledit dispositif comprenant : (a) une gaine de capteur rigide creuse allongée 20 comportant une extrémité proximale 21, une extrémité distale 22 et un canal central traversant la gaine dun bout à lautre, lextrémité distale 22 de la gaine 20 étant suffisamment pointue pour perforer une barrière cutanée et la gaine 20 ayant une longueur suffisante pour lui permettre de pénétrer dans lespace intravasculaire dun vaisseau sanguin (b) une fibre optique souple 30 ayant u
