Elena CASALE,Emliana CORTI,Paola GNOCCHI,Marcella NESI,Sten Christian ORRENIUS,Francesca QUARTIERI,Federico RICCARDI SIRTORI
申请号：
US16319951
公开号：
US20190225615A1
申请日:
2017.07.19
申请国别(地区):
US
年份:
2019
代理人:
摘要：
There are provided substituted purine and 3-deazapurine analogues, which modulate the activity of Choline Kinase (ChoK). The compounds of this invention are therefore useful in treating diseases caused by an altered choline metabolism, such as cancer, cell proliferative disorders, infectious diseases of different origin, immune-related disorders and neurodegenerative disorders. The present invention also provides methods for preparing these compounds, pharmaceutical compositions comprising these compounds, and methods of treating diseases utilizing pharmaceutical compositions comprising these compounds.
