2-phenyl-N-(pyridine-hydroxymethyl) cyclopropane compounds, acryloyl choline acrylic choline receptor n-acrylonitrile modulator (PAMS); pharmaceutical ingredients; and compounds for the treatment of specific diseases such as psychosis, schizophrenia, C disorder, etc. There are others.
The present invention relates to phenylcyclopropane carboxamide derivatives of formula (I) useful in therapy, to compositions comprising said compounds, and to their medical use. The compounds referred to are positive allosteric modulators (PAMs) of the nicotinic acetylcholine ±7 receptor useful for the treatment of diseases and conditions such as schizophrenia, Alzheimers's, Parkinson's and epilepsy.COMPUESTOS DERIVADOS DE 2-FENIL-N-(PIRIDIN-HIDROXIMETIL)CICLOPROPANOCARBOXAMIDA, MODULADORES ALOSTÉRICOS POSITIVOS (PAMs) DEL RECEPTOR NICOTÍNICO DE ACETILCOLINA alfa7; COMPOSICIÓN FARMACÉUTICA; Y USO PARA EL TRATAMIENTO DE UNA ENFERMEDAD SELECCIONADA ENTRE PSICOSIS, ESQUIZOFRENIA, TRASTORNOS COGNITIVOS, ENTRE OTROS.