Noll, Bernhard O.,Krieg, Arthur M.,Vollmer, Joerg,Uhlmann, Eugen
申请号：
AU2004285561
公开号：
AU2004285561C1
申请日:
2004.10.29
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The invention relates to a class of CpG immunostimulatory oligonucleotides containing a CpG immunostimulatory motif and a second motif which is capable of forming secondary structure, including duplex and higher order structures, in vitro and in vivo. The oligonucleotides of the invention are useful as adjuvants in vaccination. The oligonucleotides are also useful for inducing an immune response, inducing expression of a type I interferon (IFN), inducing expression of gamma interferon (IFN-γ), and for treating a variety of conditions, including allergy, asthma, infection, and cancer.
