抗體調配物农业专利-农业专业知识服务系统

发明人:: GOKARN, YATIN R.,钩卡恩　亚停Ｒ,鉤卡恩　亞停Ｒ,KAMERZELL, TIMOTHY J.,坎莫载尔　提摩西Ｊ,坎莫載爾　提摩西Ｊ,LI, MEGAN,李梅根,CROMWELL, MARY,克兰威尔　玛莉,克蘭威爾　瑪莉,LIU, HONG,刘泓,劉泓,钩卡恩亚停R,鉤卡恩亞停R,坎莫载尔提摩西J,坎莫載爾提摩西J,克兰威尔玛莉,克蘭威爾瑪莉

摘要：: The invention provides a stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.0 to about 6.0, and an optional surfactant, methods for making such a formulation, and methods of using such a formulation.本發明提供一種穩定含水醫藥調配物，其包含治療有效量之抗體，視情況未經預先冷凍乾燥，維持pH在約4.0至約6.0範圍內的緩衝液，及視情況選用之界面活性劑；製備該調配物之方法，及使用該調配物之方法。