DATE HIROSHI,伊達 洋至,YOSHIKAWA TOYOFUMI,芳川 豊史,TANAKA RINA,田中 里奈
申请号：
JP2015185848
公开号：
JP2017057184A
申请日:
2015.09.18
申请国别(地区):
JP
年份:
2017
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a composition that effectively alleviates ischemia-reperfusion injury.SOLUTION: According to the present invention, in one embodiment, the composition for alleviating ischemia-reperfusion injury comprises a c-Abl tyrosine kinase inhibitor. The composition for alleviating ischemia-reperfusion injury may be a solid organ preservation solution. The composition for alleviating ischemia-reperfusion injury may be an agent for alleviating ischemia-reperfusion injury to be administered to a patient in solid organ transplantation, thromboembolism, and surgery involving blocking at least a portion of blood flow to an organ or tissue.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】虚血再灌流障害を効果的に軽減する組成物を提供する。【解決手段】本発明の一実施形態に係る虚血再灌流障害軽減用組成物は、c-Ablチロシンキナーゼ阻害剤を含む。前記虚血再灌流障害軽減用組成物は、固形臓器保存液であってもよい。また、前記虚血再灌流障害軽減用組成物は、固形臓器移植、血栓塞栓症、及び臓器又は組織への血流の少なくとも一部の遮断を伴う手術のいずれかにおいて患者に投与される虚血再灌流障害軽減剤であってもよい。【選択図】図1
