DE BRUYN, MARCEL FRANS LEOPOLD,戴玛斯,戴瑪斯,MACDONALD, GREGOR JAMES,马乔志,馬喬志,KENNIS, LUDO EDMOND JOSEPHINE,康卢度,康盧度,LANGLOIS, XAVIER JEAN MICHEL,蓝麦克,藍麥克,VAN DEN KEYBUS, FRANS ALFONS MARIA,范法兰,范法蘭,VAN ROOSBRO
申请号：
TW095139268
公开号：
TWI399373B
申请日:
2006.10.25
申请国别(地区):
TW
年份:
2013
代理人:
摘要：
The present invention relates to compounds that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, for example schizophrenia, by exerting an antipsychotic effect without motor side effects.本發明係關於快速解離多巴胺2受體拮抗劑的化合物,製備此等化合物的方法,包含此等化合物作為活性組成份之醫藥組成物。該化合物發現藉由發揮無運動副作用之抗精神病效益作為治療或預防中樞神經系統障礙,例如精神分裂症之醫藥品的效用。
