Langlois, Xavier Jean Michel,Van Gool, Michiel Luc Maria,Bartolome-Nebreda, Jose Manuel,Macdonald, Gregor James
申请号:
AU2008214716
公开号:
AU2008214716B2
申请日:
2008.02.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The present invention relates to 4-aryl-6-piperazin-1-yl-3-substituted-pyridazines that are fast dissociating dopamine 2 receptor antagonists, processes for preparing these compounds, pharmaceutical compositions comprising these compounds as an active ingredient. The compounds find utility as medicines for treating or preventing central nervous system disorders, forexample schizophrenia, by exerting an antipsychotic effect without motor side effects.