A multi-lumen tube set is disclosed for use during a laparoscopic surgical procedure performed within a patient's abdominal cavity, which includes at least a first lumen configured to extend between a first surgical access port accessing the patient's abdominal cavity and an external vacuum source, and a branching conduit communicating with the first lumen and configured for connection to a second surgical access port accessing the patient's abdominal cavity to facilitate smoke evacuation from the patient's abdominal cavity during a laparoscopic surgical procedure.