JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO.; LTD.
发明人:
Dongfang SHI,Changjin FU,Xi CHENG,Jianghua ZHU
申请号:
US15572760
公开号:
US20180134673A1
申请日:
2016.05.06
申请国别(地区):
US
年份:
2018
代理人:
摘要:
It discloses compounds for the treatment and prevention of breast cancer, which are specifically 2-phenyl benzoselenazole compounds, pharmaceutically acceptable salts thereof and prodrugs thereof. The present invention further discloses pharmaceutical compositions containing the compounds and applications of the compounds in preparing medicines for the treatment and prevention of breast cancer in mammals. The compounds of the present invention can effectively inhibit or reduce the growth or proliferation of breast cancer cells in mammals, with no inhibition effect on the growth of part of the tested cell lines except for the breast cancer cell lines, and are highly selective.