Jay Gregory Calvert,Monica Balasch,Maria Fort,Douglas S. Pearce,Marcia L. Keith
申请号：
US16469321
公开号：
US20190365881A1
申请日:
2017.12.14
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides modified live European PRRS viruses (whether or not recombinant) that have been at all times cultured, maintained, and/or attenuated on non-simian cells, typically porcine cells, wherein such cells express a porcine CD163 receptor, and whereinby vaccines prepared from such viruses are safe and efficacious, and permit the pre-weaning single dose vaccination of swine, typically as early as Day 1 of life.
