Yong Tae Kim,Zahi Fayad,Willem J. Mulder,Edward Fisher,Fay Francois,Omid C. Farokhzad,Robert Langer
申请号：
US14409264
公开号：
US20150182461A1
申请日:
2013.06.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Methods for making particles, such as nanoparticles, devices useful in the methods, and particles made by the method are described herein. The methods involves the use of a microfluidic device, such that upon mixing solutions of the materials to form the particles (or a solution of the material or materials to form the particles and a non-solvent for the material or materials), at least two symmetrical microvortices are formed simultaneously. The method can be used to prepare polymeric or non-polymeric particles and hybrid particles, such as lipid-polymer hybrid particles, as well as such particles containing one or more agents associated with the particles.
