Yong Tae Kim,Zahi Fayad,Willem J. Mulder,Edward Fisher,Francois Fay,Omid C. Farokhzad,Robert Langer
申请号：
US15617557
公开号：
US20170333348A1
申请日:
2017.06.08
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Methods for making particles, such as nanoparticles, devices useful in the methods, and particles made by the method are described herein. The methods involves the use of microfluidic device, such that upon mixing solutions of the materials to form the particles (or a solution of the material or materials to form the particles and a non-solvent for the material or materials) at least two symmetrical microvortices are formed simultaneously. The method can be used to prepare polymeric or non-polymeric particles and hybrid particles, such as lipid-polymer hybrid particles, as well as such particles containing one or more agents associated with the particles.
