GOEHRING, R. RICHARD,TAFESSE, LAYKEA,YOUNGMAN, MARK A.
申请号:
CA2894967
公开号:
CA2894967A1
申请日:
2013.12.13
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The application is directed to compounds of Formula (I'-?), and especially to compounds of Formula (I-A) and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula (I'-?), and especially compounds of Formula (I-A), to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.