PHENYLPROPIONAMIDE COMPOUNDS AND THE USE THEREOF

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专利权人:

PURDUE PHARMA LP

发明人:

ZHOU XIAOMING

申请号：

SI200730992

公开号：

SI2079485T1

申请日:

2007.10.31

申请国别(地区):

SI

年份:

2012

代理人:

摘要：

The invention relates to phenylpropionamide compounds of Formula I: and pharmaceutically acceptable salts, prodrugs, and solvates thereof, wherein A, B, R 1 , R 2 , R 3 , R 4 and R 5 are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the activation of opioid receptors, particularly µ-opioid receptors. Compounds of the present invention are especially useful for treating pain.

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