Wrobleski, Stephen T.,Brown, Gregory D.,Lin, Shuqun,Duan, Jingwu,Lu, Zhonghui,Dhar, T.G. Murali,Xiao, Hai-Yun,Tebben, Andrew J.
申请号：
AU2016233289
公开号：
AU2016233289A1
申请日:
2016.03.17
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is N W is: -(CR3R3)2-5-, -(CR3R3)x-Y-(CR3R3)y-, -Y-(CR3R3)2-3-Y-, -CR3R3-Y-(CR3R3)2-Y-,-Y-(CR3R3)2-Y-CR3R3- and Y, R1, R2, R3, R5, R6, R8, x, and y are define herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
