WROBLESKI STEPHEN T,BROWN GREGORY D,LIN SHUQUN,DUAN JINGWU,LU ZHONGHUI,DHAR T G MURALI,XIAO HAI YUN,TEBBEN ANDREW J
申请号:
IN201717036519
公开号:
IN201717036519A
申请日:
2017.10.13
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
Disclosed are compounds of Formula (I) or a salt thereof, wherein: X is N W is: -(CR3R3)2-5-, -(CR3R3)x-Y-(CR3R3)y-, -Y- (CR3R3)2-3-Y-, -CR3R3-Y-(CR3R3)2-Y-,-Y-(CR3R3)2-Y-CR3R3- and Y, R1, R2, R3, R5, R6, R8, x, and y are define herein. Also disclosed are methods of using such compounds as modulators of TNFα, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.