Ravindra Kumar,Asya Grinberg,Dianne S. Sako,Roselyne Castonguay,Rita Steeves
申请号:
US15044883
公开号:
US09809637B2
申请日:
2016.02.16
申请国别(地区):
US
年份:
2017
代理人:
摘要:
In certain aspects, the present disclosure relates to polypeptides comprising a truncated, ligand-binding portion of the extracellular domain of TβRII polypeptide useful to selectively antagonize a TβRII ligand. The disclosure further provides compositions and methods for use in treating or preventing TGFβ associated disorders.