ROBBINS, DAVID,REZNER, BETSY,MITCHELL, LEAH,GUERRETTAZ, LISA,PARONE, PHILIPPE ALESSANDRO,TACKE, ROBERT STEVEN,LAI, KEVIN,VALAMEHR, BAHRAM
申请号:
CA2974903
公开号:
CA2974903A1
申请日:
2016.01.26
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention is directed to compositions and methods to increase the expression of PD-L1 and/or IDO-1 in a population of cells, the modulated cells expressing increased PD-L1 and/or IDO-1, and methods related to the immunosuppressive effects obtained by cells expressing increased PD-L1 and/or IDO-1.