MINUTOLO FILIPPO,GRANCHI CARLOTTA,GIANNACCINI GINO,MACCHIA MARCO,ROY SARABINDU,LUCACCHINI ANTONIO
申请号:
ZA201203993
公开号:
ZA201203993B
申请日:
2012.05.31
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
The present invention concerns compounds, some of which are novel, and their pharmaceutical applications. The compounds of the invention inhibit the enzyme lactate dehydrogenase (LDH) involved both in the metabolic process of hypoxic tumour cells, and in the process used by parasitic protozoa that cause malaria to obtain most of the energy they need.