Minutolo, Filippo,Macchia, Marco,Granchi, Carlotta,Roy, Sarabindu,Giannaccini, Gino,Lucacchini, Antonio
申请号:
AU2010314367
公开号:
AU2010314367A1
申请日:
2010.11.05
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The present invention concerns compounds, some of which are novel, and their pharmaceutical applications. The compounds of the invention inhibit the enzyme lactate dehydrogenase (LDH) involved both in the metabolic process of hypoxic tumour cells, and in the process used by parasitic protozoa that cause malaria to obtain most of the energy they need.