Chih-Cheng Chen,Yun-Lian Lin,Jim-Min Fang,Yijuang Chern,Chia-Ching John Lin,Wei-Nan Chen,Chun-Jung Lin
申请号:
US14378013
公开号:
US20150038445A1
申请日:
2013.02.11
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The disclosure provides a new use of adenosine analogs for the treatment of pain through activation of neurokinin 1 (NK1) receptor signaling pathway, thereby inducing the activation of M-type potassium channel to induce outward currents. A method and pharmaceutical composition for treating pain comprising an adenonsine analog that activates NK1 receptor signaling, thereby inducing outward current are also provided.