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Compounds with anti-cancer activity
专利权人:
CanBas Co.; Ltd.
发明人:
KAWABE, Takumi,ISHIGAKI, Machiyo,SATO, Takuji,YAMAMOTO, Sayaka,HASEGAWA, Yoko
申请号:
ES08829410
公开号:
ES2594704T3
申请日:
2008.04.11
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
Compound presenting the formula of: ** Formula ** in which R1 and R2 are independently selected from alkyl, substituted alkyl, optionally substituted alkoxy, optionally substituted alkythium, optionally substituted aryloxy, or optionally substituted anitium, where when X it is not O, R1 and R2 can also be part of a cyclic alkylene chain that forms a fused ring structure; X is O, S, or NR3; when X is NR3, Ar is not phenyl; aryl or aryl substituted on the optionally substituted aryloxy or optionally substituted arithium includes carbocyclic aryl, tererocyclic aryl, monocyclic aryl, polycyclic aryl, and non-aryl ring fused aryl (non-aromatic): R3 is H. alkyl, substituted alkyl, optionally substituted acyl , or as part of a ring structure that connects N to the Ar ring; A is N or CH; B is CR8, and R6, R7, R8, and R9 are independently selected from H, alkyl, substituted alkyl, halogen, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted alkoxy, optionally substituted aryloxy, cyano, nitro, optionally substituted alkythio, optionally substituted alkylsulfonyl, carboxyl, optionally substituted alkoxycarbonyl, optionally substituted carbomoyl, wherein R6 and R7, or R7 and R8, or R8 and R9 may be part of a cyclic alkylene group that forms a fused ring structure; or a salt thereof; in which in addition the compound does not present the following structure: ** Formula **Compuesto que presenta la fórmula de:**Fórmula** en el que R1 y R2 se seleccionan independientemente de entre alquilo, alquilo sustituido, alcoxi opcionalmene sustituido, alquitio opcionalmente sustituido, ariloxi opcionalmente sustituido, o anitio opcionalmente sustituido, en la que cuando X no es O, R1 y R2 pueden asimismo ser parte de una cadena de alquileno ciclica que forma una estructura de anillo condensado; X es O, S, o NR3; cuando X es NR3, Ar no es fenilo; arilo o arilo sustituido en el ariloxi opcionalmente sustituido o aritio opcionalmente sustituido incluye arilo
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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