您的位置: 首页 > 农业专利 > 详情页

DERIVATIVES OF DOLASTATIN 10 AND AURISTATINS
专利权人:
发明人:
Michel PEREZ,Ian RILATT,Marie LAMOTHE
申请号:
US14786921
公开号:
US20160083420A1
申请日:
2014.04.25
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention concerns a compound of following formula (I) where: —R1 is H or OH, —R2 is a (C1-C6)alkyl, COOH, COO—((C1-C6)alkyl) or thiazolyl group, —R3 is H or a (C1-C6)alkyl group, and —R4 is: —an aryl-(C1-C8)alkyl group substituted by one or more groups chosen from among OH and NR9R10 groups, or —a heterocycle-(C1-C8)alkyl group optionally substituted by one or more groups chosen from among (C1-C6)alkyl, OH and NR12R13 groups, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and its uses in particular for the treatment of cancer, pharmaceutical compositions containing the same and the preparation methods thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充