The present invention concerns a compound of following formula (1): where: - R1 is H or OH, - R2 is a (C1-C6)alkyl, COOH, COO-((C1-C6)alkyl) or thiazolyl group, - R3 is H or a (C1-C6)alkyl group, and - R4 is: • a straight-chain or branched, saturated or unsaturated hydrocarbon group having l to 8 carbon atoms substituted by one or more groups chosen from among OH and NR5R6, • -(CH2CH2X1)(CH2CH2X2)a2(CH2CH2X3)a3(CH2CH2X4)a4(CH2CH2X5)a5R7, • an aryl-(C1-C8)alkyl group substituted by one or more groups chosen from among OH and NR9R10 groups, or • a heterocycle-(C1-C8)alkyl group optionally substituted by one or more groups chosen from among (C1-C5)allcyl, OH and NR12R13 groups, or a phammceutically acceptable salt, hydrate or solvate thereof, and its uses in particular for the treatment of cancer, pharmaceutical compositions containing the same and the preparation methods thereof.
