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FORMES CRISTALLINES DE SEL DE MESYLATE DE DERIVE DE PYRIDINYL-AMINOPYRIMIDINE, PROCEDES DE PREPARATION ET APPLICATIONS ASSOCIES
专利权人:
INC.;SHANGHAI ALLIST PHARMACEUTICALS;SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECHNOLOGY CORPORATIONS
发明人:
LUO, HUIBING,ZHANG, QIANG
申请号:
CA3016830
公开号:
CA3016830A1
申请日:
2017.03.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides crystalline form I and crystalline form II of a mesylate salt of a pyridinyl amino pyrimidine derivative and preparation methods therefor, a pharmaceutical composition containing the crystalline forms, and applications of the crystalline forms in the treatment of activated EGFR mutant- or drug-resistant mutant-mediated diseases, especially cancer, in mammals, particularly humans. The crystalline forms of the mesylate salt of the compound represented by formula (I) have good solubility and high bioavailability in animals.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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