INC.;SHANGHAI ALLIST PHARMACEUTICALS;SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECHNOLOGY CORPORATIONS
发明人:
LUO, HUIBING,ZHANG, QIANG
申请号:
CA3016830
公开号:
CA3016830A1
申请日:
2017.03.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
The present invention provides crystalline form I and crystalline form II of a mesylate salt of a pyridinyl amino pyrimidine derivative and preparation methods therefor, a pharmaceutical composition containing the crystalline forms, and applications of the crystalline forms in the treatment of activated EGFR mutant- or drug-resistant mutant-mediated diseases, especially cancer, in mammals, particularly humans. The crystalline forms of the mesylate salt of the compound represented by formula (I) have good solubility and high bioavailability in animals.