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SEL DE DERIVE DE PYRIDINYL AMINO PYRIMIDINE, SON PROCEDE DE PREPARATION ET SON APPLICATION
专利权人:
INC.;SHANGHAI ALLIST PHARMACEUTICALS;SHANGHAI ALLIST PHARMACEUTICAL AND MEDICAL TECHNOLOGY CORPORATIONS
发明人:
LUO, HUIBING,ZHOU, HUAYONG
申请号:
CA3016826
公开号:
CA3016826A1
申请日:
2017.03.01
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A mesylate salt of a compound represented by formula (I) and preparation method therefor, a pharmaceutical composition containing the salt, and an application of the salt in the treatment of activated EGFR mutant- or drug-resistant mutant-mediated diseases, especially cancer, in mammals, particularly humans. The mesylate salt of the compound represented by formula (I) has high bioavailability in animals, can better inhibit the growth of transplanted tumors in animals, and demonstrates desirable safety.
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