Donald Landry;Patricia F. Ducy;Yuli Xie;Gerard Karsenty;Vijay Kumar Yadav
发明人:
Gerard Karsenty,Patricia F. Ducy,Yuli Xie,Donald Landry,Vijay Kumar Yadav
申请号：
US12935651
公开号：
US08759364B2
申请日:
2009.03.30
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides methods and therapeutic agents for lowering or increasing serum serotonin levels in a patient in order to increase or decrease bone mass, respectively. In preferred embodiments, the patient is known to have, or to be at risk for, a low bone mass disease such as osteoporosis and the agents are TPH1 inhibitors or serotonin receptor antagonists.
