compound, process for the preparation of the compound, method for the treatment of a central nervous system disorder related to or affected by the 5-ht6 receptor, pharmaceutical composition, use of the compound and method for testing receptor-selective antagonists and antagonists 5- ht6
COMPOUND, PROCESS FOR PREPARATION OF COMPOUND, METHOD FOR TREATMENT OF A CENTRAL NERVOUS SYSTEM DISORDER RELATED TO OR AFFECTED BY THE 5-HT_6 RECEPTOR, COMPOSITE COMPOSITION AND ANTI-ANTESTANT SELECTED TESTING FOR THE ANTESTANT TEST. The present invention relates to carbazole derivatives of formula (I) useful in the treatment of a CNS disorder related to or affected by the 5-HT6 receptor. The pharmacological profile of said compounds includes a high affinity binding to the 5-HT6 receptor associated with good selectivity with respect to said receptor. The present invention further includes stereoisomers, salts, methods of preparation and medicaments containing said carbazole derivatives.COMPOSTO, PROCESSO PARA A PREPARAÇçO DO COMPOSTO, MÉTODO PARA O TRATAMENTO DE UMA DESORDEM DO SISTEMA NERVOSO CENTRAL RELACIONADAS A OU AFETADA PELO RECEPTOR 5-HT_6, COMPOSIÇçO FARMACÊUTICA, USO COMPOSTO E MÉTODO PARA TESTAR ANTAGONISTAS E ANTAGONISTAS COM SELETIVIDADE PARA O RECEPTOR HT_6. A presente invenção refere-se a derivados de carbazola de fórmula (I), úteis no tratamento de uam desordem do SNC relacionada a ou afetada pelo receptor 5-HT_6. O perfil farmacol´´ogico dos referidos compostos inclui uma ligação de alta afinidade com o receptor 5-HT_6 associada a uma boa seletividade com relação ao referido receptor. A presente invenção inclui ainda os estereoisômeros, os sais, métodos de preparação e os medicamentos contendo os referidos derivados de carbazola.
