LI Khetszin,ЛИ Хэцзинь,DENIEL Karen,ДЕНИЭЛ Карен,SENSOUN Mettyu,СЭНСОУН Мэттью
申请号：
RU2015139934
公开号：
RU2666684C2
申请日:
2014.03.17
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
FIELD: medicine.SUBSTANCE: group of inventions includes the intravesical drug delivery device, and the drug to the patient controlled release provision method, relates to the field of medicine, and is intended for the drug release for therapeutic treatment. Intravesical drug delivery device comprises housing, comprising the drug reservoir closed cavity, limited by the first wall structure from the first material and the hydrophilic second wall structure from the second material, and the medicament contained in the drug reservoir cavity. First wall structure is made impermeable to the medicament, and the second wall structure is made permeable to the medicament. First wall structure is the cylindrical tube, and the second wall structure is the end wall, disposed at least on one end of the cylindrical tube, or the first wall structure and the second wall structure are adjacent to each other, and together form the cylindrical tube. First and second materials hardness is selected to make the device susceptible in the patients bladder. Drug to the patient controlled release provision method consists in the fact, that deploying the drugs delivering device in the patients body, wherein the said device comprises the drug reservoir closed cavity, limited by the first wall structure from the first material and the hydrophilic second wall structure from the second material, and releasing the drug from the drug reservoir cavity by penetration through the second wall structure.EFFECT: inventions allow the drugs delivery inside the bladder with effective release rates for the certain group of different drugs over the long period of time and pain relief during the device deployment in the bladder cavity.26 cl, 37 dwgГруппа изобретений включает внутрипузырное устройство для доставки лекарственных средств и способ обеспечения управляемого высвобождения лекарственного средства в пациента, относится к области медицины и предназначена для высвобождения лекарственного средства для терап
