VU CHI B,DISCH JEREMY S,NG PUI YEE,BLUM CHARLES A,PERNI ROBERT B
申请号:
ZA201009170
公开号:
ZA201009170B
申请日:
2010.12.21
申请国别(地区):
ZA
年份:
2014
代理人:
摘要:
Provided herein are sirtuin-modulating compounds of formula (II). The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders relating to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.