Vu, Chi B.,Perni, Robert B.,Ng, Pui Yee,Blum, Charles A.,Disch, Jeremy S.
申请号:
AU2009266889
公开号:
AU2009266889B2
申请日:
2009.07.02
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Provided herein are sirtuin-modulating compounds of formula (II) The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.