This invention, consecutive condition such as the heartburn and the gastralgia which are based on the gastric hyperacidety which does not utilize the anti- pylori germ operation of the lactobacillus, designates that the new medicine or the food which it prevents improves of the counterflow Characteristic esophagus flame and the esophagus cancer/gun etc is offered as topic. This invention includes the dead fungus body of the Lactobacillus being attached bacterium, it regards the gastrin production restrainer and the food constituent which contains that. As for especially main invention, the Lactobacillus being attached bacterium, Lactobacillus gasseri (especially, Lactobacillus gasseri OLL2716) regards the gastrin production restrainer which is.本発明は、乳酸菌の抗ピロリ菌作用を利用しない胃酸過多に基づく胸焼け、胃痛等の一連の症状、逆流性食道炎、食道ガンなどの予防改善する新たな医薬または食品を提供することを課題とする。本発明は、ラクトバチルス属細菌の死菌体を含む、ガストリン産生抑制剤およびそれを含有する食品組成物に関する。とくに本発明は、ラクトバチルス属細菌が、Lactobacillus gasseri(とくに、Lactobacillus gasseri OLL2716)であるガストリン産生抑制剤に関する。
