PURPOSE: An anti-coccidial composition containing medicinal herb material extract is provided to lower a mortality rate of livestock and to prevent drug resistance and drug residual. CONSTITUTION: An anti-coccidial composition contains a mixture extract of Siegesbeckiae Herba, Scutellariae Radix, Clematidis Radix, Artemisiae apiaceae Herba, Pulsatillae Radix, and Aurantii nobilis Pericarpium. The extract is prepared using one or more solvents selected from a group consisting of water, ethanol, and butanol. [Reference numerals] (AA) Pulverizing the ingredients of medicinal herbs; (BB) Ethanol adding, mixing, and extracting; (CC) Drying; (DD) Adding microorganism and vitamin and mixing; (EE) Filling, packaging, (powder)본 발명은 황금, 위령선, 청호, 백두옹, 목진피, 및 희렴초의 혼합 추출물을 포함하는, 항콕시듐 조성물에 관한 것이다.