CLAIBORNE, CHRISTOPHER F.,CRITCHLEY, STEPHEN,LANGSTON, STEVEN P.,OLHAVA, EDWARD J.,PELUSO, STEPHANE,WEATHERHEAD, GABRIEL S.,VYSKOCIL, STEPAN,VISIERS, IRACHE,MIZUTANI, HIROTAKE,CULLIS, COURTNEY
申请号:
CA2659894
公开号:
CA2659894C
申请日:
2007.08.06
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders; and inflammation associated with infection and cachexia.