CRITCHLEY, STEPHEN,GANT, THOMAS G.,LANGSTON, STEVEN P.,OLHAVA, EDWARD J.,PELUSO, STEPHANE
申请号：
CA2596424
公开号：
CA2596424C
申请日:
2006.02.02
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
This invention relates to compounds of the general formula I-A orpharmaceuticallyacceptable salts thereof, that inhibit E1 activating enzymes, pharmaceuticalcompositionscomprising the compounds, and methods of using the compounds. The compoundsareuseful for treating disorders, particularly cell proliferation disorders,including cancers,inflammatory and neurodegenerative disorders； and inflammation associated withinfection and cachexia.(see above formula)
