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PYRROLOBENZODIAZEPINES ET CONJUGUES CIBLES
专利权人:
SEATTLE GENETICS, INC.;SPIROGEN SARL
发明人:
JEFFREY, SCOTT,BURKE, PATRICK,HOWARD, PHILIP WILSON
申请号:
CA2850373
公开号:
CA2850373C
申请日:
2012.10.12
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
A compound, or a pharmaceutically acceptable salt or solvate thereof, or conjugates thereof, selected from the group consisting of formula wherein: (a) R10 is H, and R11 is OH, ORA, where RA is saturated C1-4 alkyl; (b) R10 and R11 form a nitrogen-carbon doub!e bond between the nitrogen and carbon atoms to which they are bound; or (c) R10 is H and R11 is S02M, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation, or both M together are a divalent pharmaceutically acceptable cation.
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